Antimicrobial Surfaces from Incorporated Nano-agents

MUNICOY, SOFÍA; BELLINO, MARTÍN GONZALO; DESIMONE, MARTÍN FEDERICO; CATALANO, PAOLO NICOLÁS

Current Bionanotechnology

Bentham Science Publishers

Año: 2016 vol. 1 p. 125 - 134

Biofilm development is a survival strategy formajority of bacteria to adapt to their living environment. These biofilms areprevalent on most surfaces in nature. Microbial cells in biofilm exhibitsignificantly enhanced tolerance and resistance to antimicrobial challenge andhost defenses. Therefore, the control and eradication of biofilm-associateddiseases present a great challenge. Recently, there is considerable biomedicalincentive in the development of nanoparticles with self-antibacterial activityor as antibiotic carriers. The advantages of coatings incorporating differenttypes of nano-agents for antimicrobial surface generation are here reviewed.Although the main coatings currently used or investigated and the associatedsynthesis processes are individually described, emphasis is made onsilver-loaded mesoporous thin coatings. Recent developments suggest thatmesoporous oxide thin films (especially titania) incorporating metal nanoparticlesis becoming a prime candidate for antimicrobial coatings.