Study of the Potential Value of Ilex affinis (Aquifoliaceae) as a Novel Source for the Food and Pharmaceutical Industries

LAURA COGOI; RENZO MARTINO; GUSTAVO GIBERTI; CLAUDIA ANESINI; ROSANA FILIP

Journal of Life Sciences

David Publishing Company

Año: 2014 vol. 8 p. 10 - 14

1934-7391

Abstract: Ilex paraguariensis St. Hilaire (Aquifoliaceae) is processed industrially to produce the commercial product ?yerba mate? which is used as a tea-like beverage. It is one of the most commercialized plants of South America. It is exported to the US, Europe and Asia as vegetal drug or extracts used in complementary and alternative medicine and in formulations for functional foods due to its properties as a CNS stimulant, diuretic, weight reducing, antioxidant and antihypercholesterolemic, among others. Ilex affinis which is used as a tea-like beverage. It is one of the most commercialized plants of South America. It is exported to the US, Europe and Asia as vegetal drug or extracts used in complementary and alternative medicine and in formulations for functional foods due to its properties as a CNS stimulant, diuretic, weight reducing, antioxidant and antihypercholesterolemic, among others. Ilex affinis which is used as a tea-like beverage. It is one of the most commercialized plants of South America. It is exported to the US, Europe and Asia as vegetal drug or extracts used in complementary and alternative medicine and in formulations for functional foods due to its properties as a CNS stimulant, diuretic, weight reducing, antioxidant and antihypercholesterolemic, among others. Ilex affinis Ilex paraguariensis St. Hilaire (Aquifoliaceae) is processed industrially to produce the commercial product ?yerba mate? which is used as a tea-like beverage. It is one of the most commercialized plants of South America. It is exported to the US, Europe and Asia as vegetal drug or extracts used in complementary and alternative medicine and in formulations for functional foods due to its properties as a CNS stimulant, diuretic, weight reducing, antioxidant and antihypercholesterolemic, among others. Ilex affinisIlex affinis grows in the same habitat and is used as substitute or adulterant of I. paraguariensis. This species was never investigated before. The objective of this work was to assess the phytochemical composition and to determine the pharmacological activity, according with the major compounds present in it. The results showed small quantities of caffeine and theobromine, but a considerable amount of polyphenols, especially chlorogenic acid and isochlorogenic acid. I. affinis extracts presented scavenging activity on free radical DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. objective of this work was to assess the phytochemical composition and to determine the pharmacological activity, according with the major compounds present in it. The results showed small quantities of caffeine and theobromine, but a considerable amount of polyphenols, especially chlorogenic acid and isochlorogenic acid. I. affinis extracts presented scavenging activity on free radical DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. objective of this work was to assess the phytochemical composition and to determine the pharmacological activity, according with the major compounds present in it. The results showed small quantities of caffeine and theobromine, but a considerable amount of polyphenols, especially chlorogenic acid and isochlorogenic acid. I. affinis extracts presented scavenging activity on free radical DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. I. paraguariensis. This species was never investigated before. The objective of this work was to assess the phytochemical composition and to determine the pharmacological activity, according with the major compounds present in it. The results showed small quantities of caffeine and theobromine, but a considerable amount of polyphenols, especially chlorogenic acid and isochlorogenic acid. I. affinis extracts presented scavenging activity on free radical DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated. I. affinis extracts presented scavenging activity on free radical DPPH in a concentration-dependent manner. Antiproliferative action on lymphoma cell line exerting both cytostatic and cytotoxic activities was also demonstrated.