UMYMFOR 05516
UNIDAD DE MICROANALISIS Y METODOS FISICOS EN QUIMICA ORGANICA
Unidad Ejecutora - UE
artículos
Título:
New Cytotoxic Cucurbitacins from Wilbrandia ebracteata Cogn.
Autor/es:
LANG, K. L.; DA ROSA GUIMARAES T.; ROCHA MACHADO V.; ZIMMERMANN L. A.; SILVA I.T.; TEIXEIRA M. R.; DURAN F.J.; PALERMO J. A.; SIMOES C. M. O.; CARO, M. S. B.; SCHENKEL E. P.
Revista:
PLANTA MEDICA
Editorial:
GEORG THIEME VERLAG KG
Referencias:
Lugar: Stuttgart; Año: 2010
ISSN:
0032-0943
Resumen:
Chemical investigation of the roots of Wilbrandia ebracteata Cong. (Cucurbitaceae) led to the isolation of two new and four known cucurbitacins. Their structures were elucidated by NMR and MS and compared with related compounds. The in vitro cytotoxicity of isolated compounds was evaluated againts RD, KB, HCT-8 and A549 cell lines showing strong activity
