Fernene triterpenoids from the lichen Pyxine berteriana

M.S. MAIER; M. L. ROSSO; A.T. FAZIO; M.T. ADLER; M.D. BERTONI

JOURNAL OF NATURAL PRODUCTS

AMER CHEMICAL SOC

Año: 2009 vol. 72 p. 1092 - 1094

0163-3864

Two new fernene triterpenoids, fern-9(11)-en-3,19-dione (1) and 3b-acetoxyfern-9(11)-en-19-one (2), together with the known 3b-acetoxyfern-9(11)-en-19b-ol (3) and lichexanthone (4), have been isolated from the acetone extract of the lichen Pyxine berteriana. The structures of the new compounds were established on the basis of IR, extensive 1D and 2D NMR and MS analyses. Although several fern-9(11)-enes have been isolated from lichens, compounds 1 and 2 are the first examples of naturally occurring fernene triterpenoids with a carbonyl function at C-19.