IFIBYNE 05513
INSTITUTO DE FISIOLOGIA, BIOLOGIA MOLECULAR Y NEUROCIENCIAS
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
The Impact of Retroactivity on the Signal Processing of Transduction Networks
Autor/es:
PENG JIANG; ALEJANDRA C VENTURA; SOFIA D MERAJVER; EDUARDO D SONTAG; ALEXANDER J NINFA; DOMITILLA DEL VECCHIO
Lugar:
Santa Fe
Reunión:
Conferencia; The 5th Annual q-bio Conference on Cellular Information Processing; 2011
Institución organizadora:
Los Alamos National Laboratory and Center for Nonlinear Studies
Resumen:
Retroactivity is an impedance-like effectfound at the interconnection of biomolecular systems. Just likeimpedance in electrical circuits, it causes the behavior of asystem to change upon interconnection. In this abstract, wedescribe theoretical and experimental work that characterizesthe effects of retroactivity on the dynamic behavior of signaltransduction modules. We further show how these modules canbe re-engineered to attain insulation from retroactivity.
