IFIBYNE 05513
INSTITUTO DE FISIOLOGIA, BIOLOGIA MOLECULAR Y NEUROCIENCIAS
Unidad Ejecutora - UE
capítulos de libros
Título:
CaV2.1 (P/Q) voltage activated Ca2+ channels and synaptic transmission in genetic and autoimmune diseases;
Autor/es:
UCHITEL O.D.
Libro:
Modulation of Presynaptic Calcium Channels
Editorial:
Springer
Referencias:
Lugar: New York London; Año: 2013; p. 263 - 288
Resumen:
CaV2.1 (P/Q type) Ca2+ channels have a fundamental role mediating fast transmitter release at central and peripheral synaptic terminals. Various neurological diseases have been attributed to genetic and autoimmune malfunctioning of P/Q channels, including ataxia, migraine and myasthenic syndromes. This chapter focuses on recent advances on the understanding of the pathogenic mechanisms underlying these disorders.
