CEDIE   05498
CENTRO DE INVESTIGACIONES ENDOCRINOLOGICAS "DR. CESAR BERGADA"
Unidad Ejecutora - UE
capítulos de libros
Título:
AMH in Diagnosis and Treatment of Gonadal Tumors
Autor/es:
LAMBERT-MESSERLIAN, G.; REY, R.
Libro:
Anti-Müllerian Hormone: Biology, Role in Ovarian Function and Clinical Significance
Editorial:
Nova Science Publishers
Referencias:
Año: 2015; p. 1 - 13
Resumen:
Tumor marker proteins are an important aid in the diagnosis of gonadal malignancies and are essential for monitoring disease progression in treated patients. Anti-Müllerian hormone (AMH), a member of the transforming growth factor-β family, is synthesized by granulosa cells of the ovary and Sertoli cells of the testis. AMH is useful in the differential diagnosis of sex cord-stromal tumors of the ovary and as a serum marker to monitor disease progression in women after treatment for granulosa cell tumor. AMH is also helpful to identify differentiated types of Sertoli cell tumors by immunocytochemistry. The utility of AMH as a gonadal tumor marker and potential biological roles in oncogenesis are presented in this chapter.