Thyroid disorders of neonates born to mothers with Graves´Disease. Papendieck P ,Chiesa A ,Prieto L and Gruñeiro-Papendieck L. ,22 547-553 (2009).

PAPENDIECK P ,; ,CHIESA A; PRIETO L; GRUÑEIRO-PAPENDIECK L.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY AND METABOLISM

Año: 2008 vol. 22 p. 547 - 553

2191-0251

Maternal hyperthyroidism implies the risk of thyroid abnormalities in the newborn. We describe retrospectively the clinical presenta­tion, treatment and follow up of 28 children born of hyperthyroid mothers. Patients were subdivided as follows: Group A (neonatal hyperthyroidism) (n = 9): born from eight hyperthyroid mothers and one thyroidectomized mother. Children born from untreated mothers consulted between 1 and 7 days of life, while those born from treated mothers consulted between 8 and 17 days. Eight needed treatment. All remitted completely. Group B (primary hypothyroidism) (n = 14): born from treated mothers, detected by neonatal screening. Eleven had transient hypothyroidism and three needed treatment. Group C (hypothalamic-pituitary hypothyroidism) (n = 5): born from un­controlled hyperthyroid mothers and found during follow up (age 9-28 days). The infants were treated with thyroid hormone, and recovered before 8 months of life. Every child born from a mother with autoimmune thyroid disease needs paediatric endocrinological assess­ment for detection of possible thyroid disorders