INFIQC   05475
INSTITUTO DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Unidad Ejecutora - UE
artículos
Título:
Carbon paste electrodes modified with electrogenerated magnetite and glucose oxidase. analytical applications for the highly selective and sensitive glucose biosensing
Autor/es:
FAUSTO N. COMBA, M. D. RUBIANES, L. CABRERA, SILVIA GUTIÉRREZ, PILAR HERRASTI, GUSTAVO A. RIVAS
Revista:
ELECTROANALYSIS
Editorial:
Wiley-VCH Verlang GmbH & Co, KgaA, Weinheimv
Referencias:
Lugar: Las Cruces, New México, EEUU; Año: 2010 vol. 22 p. 1566 - 1572
ISSN:
1040-0397
Resumen:
This work reports the advantages of carbon paste electrodes modified with electrogenerated magnetite nanoparticles. The nanoparticles present catalytic activity towards reduction hydrogen peroxide reduction. The incorporation of glucose oxidase (GOx) with magnetite in a carbon paste matrix have made possible the development of an efficient glucose biosensor. The effect of the amount of GOx and magnetite present in the composite on the response of the biosensor was critically evaluated. The biosensors demonstrated to be highly selective, with negligible interference of ascorbic acid and uric acid. The proposed biosensor was challenged with human blood serum demonstrating an excellent correlation with the spectrophotometric method.