INFIQC 05475
INSTITUTO DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Unidad Ejecutora - UE
artículos
Título:
An effective Pd nanocatalyst in aqueous media: Stilbene synthesis by Mizoroki-Heck coupling reaction under microwave irradiation
Autor/es:
GARCÍA, CAROLINA S.; UBERMAN, PAULA M.; MARTÍN, SANDRA E.; GARCÍA, CAROLINA S.; UBERMAN, PAULA M.; MARTÍN, SANDRA E.
Revista:
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Editorial:
BEILSTEIN-INSTITUT
Referencias:
Lugar: Frankfurt ; Año: 2017 vol. 13 p. 1717 - 1727
ISSN:
1860-5397
Resumen:
Aqueous Mizoroki-Heck coupling reactions under microwave irradiation (MW) were carried out with a colloidal Pd nanocatalyst stabilized with poly(N-vinylpyrrolidone) (PVP). Many stilbenes and novel heterostilbenes were achieved in good to excellent yields starting from aryl bromides and different olefins. The reaction was carried out in a short reaction time and with low catalyst loading, leading to high turnover frequency (TOFs of the order of 100 h-1). The advantages like operational simplicity, high robustness, efficiency and turnover frequency, the utilization of aqueous media and simple product work-up make this protocol a great option for stilbene syntheses by Mizoroki-Heck reaction.
