INFIQC 05475
INSTITUTO DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Unidad Ejecutora - UE
artículos
Título:
Withanolides from three species of the genus Deprea (Solanaceae). Chemotaxonomical considerations
Autor/es:
CASERO, C.N.; OBERTI, J.C.; OROZCO, C, I.; CÁRDENAS, A.; BRITO, I.; BARBOZA G. E.; NICOTRA, V.
Revista:
PHYTOCHEMISTRY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2015 vol. 110 p. 83 - 90
ISSN:
0031-9422
Resumen:
Nine withanolides were isolated from the aerial parts of Deprea bitteriana, Deprea cuyacensis, and Deprea zamorae. D. bitteriana yielded two withaphysalins, D. cuyacensis gave two 13,14-seco withaphysalins, while D. zamorae yielded five physangulidines. The compounds were fully characterized by a combination of spectroscopic methods (1D and 2D NMR and MS). All compounds isolated from D. bitteriana and D. cuyacensis were obtained as epimeric mixtures at C-18. The structure of physangulidine D was confirmed by X-ray diffraction analysis. The skeletons found in this research support the chemotaxonomical position of the genus Deprea in the tribe Physalideae.
