INFIQC 05475
INSTITUTO DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Unidad Ejecutora - UE
artículos
Título:
Coupling biocatalysis and click chemistry: one-pot two-step convergent synthesis of enantioenriched 123-triazole-derived diols
Autor/es:
ANÍBAL CUETOS; FABRICIO R. BISOGNO; IVÁN LAVANDERA; VICENTE GOTOR
Revista:
CHEMICAL COMMUNICATIONS
Editorial:
ROYAL SOC CHEMISTRY
Referencias:
Lugar: CAMBRIDGE; Año: 2013 vol. 49 p. 2625 - 2627
ISSN:
1359-7345
Resumen:
A fully convergent one-pot two-step synthesis of different chiral 1,2,3-triazole-derived diols in high yields and excellent enantio- and diastereoselectivities has been achieved under very mild conditions in aqueous medium by combining a single alcohol dehydrogenase (ADH) with a Cu-catalysed ?click? reaction.
