INFIQC   05475
INSTITUTO DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Unidad Ejecutora - UE
artículos
Título:
Adsorption and Electrooxidation of Nucleic Acids at Glassy Carbon Electrodes Modified with Multiwalled Carbon Nanotubes Dispersed In Polylysine
Autor/es:
YAMILE JALIT; MÓNICA MORENO; FABIANA A. GUTIERREZ; ALBERTO SANCHEZ ARRIBAS; MANUEL CHICHARRO; ESPERANZA BERMEJO; ANTONIO ZAPARDIEL; CONCEPCIÓN PARRADO; GUSTAVO A. RIVAS; MARCELA C. RODRÍGUEZ
Revista:
ELECTROANALYSIS
Editorial:
WILEY-V C H VERLAG GMBH
Referencias:
Lugar: Weinheim; Año: 2013 vol. 25 p. 1116 - 1121
ISSN:
1040-0397
Resumen:
We report the advantages of the adsorption and electrooxidation of oligonucleotides and calf-thymus double strand- ed DNA (dsDNA) at glassy carbon electrodes (GCE) modified with a dispersion of multiwalled carbon nanotubes (MWCNT) in poly-l-lysine (Plys) (GCE/MWCNT-Plys). Important enhancement in the guanine oxidation signal was obtained by adsorptive stripping voltammetry (AdSV) due to a most favorable interaction between the nega- tively charged DNAs and the positively charged Plys that support the MWCNT. The layer of oligo(dG)11 immobi- lized at GCE/MWCNT-Plys was successfully used for the selective detection of the hybridization event using oli- go(dG)11/oligo(dC)11 as model.