INFIQC   05475
INSTITUTO DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Unidad Ejecutora - UE
artículos
Título:
Synthesis of Pyrrole and Indole Quinoxalinone and Oxazinone Derivatives by Intramolecular Copper-Catalyzed Reactions
Autor/es:
VICTORIA A. VAILLARD; ROBERTO A. ROSSI; SANDRA E. MARTÍN
Revista:
ORGANIC & BIOMOLECULAR CHEMISTRY
Editorial:
ROYAL SOC CHEMISTRY
Referencias:
Año: 2011 p. 4927 - 4935
ISSN:
1477-0520
Resumen:
Intramolecular N-arylation of pyrrole and indole carboxamides and carboxylates linked with a pendant haloarenes by Cu-catalyzed reactions to synthesize pyrrole and indole quinoxalinone and oxazinone derivatives is reported. The ring closure reactions were carried out by conventional heating and MW irradiation. The use of conventional heating affords moderate to good yields of the quinoxalinone and oxazinone derivatives (34-72%), while by MW heating best result are obtained (41-99%).