INFIQC   05475
INSTITUTO DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Unidad Ejecutora - UE
artículos
Título:
A different route to 3-aryl-4-hydroxycoumarins
Autor/es:
RODRÍGUEZ, S. A.; BAUMGARTNER, M. T.
Revista:
TETRAHEDRON LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 2010
ISSN:
0040-4039
Resumen:
We here report the simple and direct arylation of 4-hydroxycoumarins by photoinduced reaction with aryl halides(iodobenzene, iodonaphthalene, 4-iodoanisole, 2-iodoanisole). Good yields of 3,4-disubstituted coumarins were obtained in these reactions(> 60%). Extension of the procedure to the reaction with o-dihalobenzenes leads to the synthesis of ring closure products which bear atetracyclic aromatic condensed ring system, although in lower overall yields ( 45%).