IMBIV 05474
INSTITUTO MULTIDISCIPLINARIO DE BIOLOGIA VEGETAL
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Photodynamic inactivation of Candida tropicalis biofilms by parietin, a natural dihydroxyanthraquinone
Autor/es:
MUGAS ML; CD BORSARELLI; MARIONI J; NUÑEZ MONTOYA S.C.
Lugar:
Viña del Mar
Reunión:
Encuentro; XIV ELAFOT; 2019
Institución organizadora:
Universidad de Santiago de Chile, Universidad Andrés Bello
Resumen:
The 1,8-dihydroxy-3-methoxy-6-methylanthraquinone (Parietin, PTN), a blue-light absorbing pigment present in several lichens of the genus Teloschistes spp., shows photosensitizing properties through both Type I (superoxide anion, O2?-) and Type II (singlet molecular oxygen, 1O2) mechanism, with antibacterial effects in vitro when it was photo-stimulated [1]. The aim of this work was to evaluate the in vitro antifungal activity of PTN, analyzing whether this effect could be increased by actinic irradiation, and establishing if the photoinactivation mechanism involves the production of Reactive Oxygen Species (ROS).
