Biocompatible and bioadhesive films based on polyelectrolyte-drug complexes using novel dendronized chitosan loaded with Ciprofloxacino

MONICA GARCIA; ALVARO JIMENEZ KAIRUZ; AGUSTINA ALDANA; MARISA MARTINELLI

Cordoba

Congreso; Reunion Internacional de Ciencias Farmaceuticas; 2014

The use of polymeric films as topical controlled drug delivery systems is an interesting alternative to conventional treatments. New dendronized chitosan derivatives (WChi) were synthesized as biomaterials with improved mechanical properties.(1) The aims of this work were the preparation of film based on Chi-Ciprofloxacino ionic complexes (Chi-Cip) and the in vitro evaluation of relevant biopharmaceutical behaviours.