IMBIV   05474
INSTITUTO MULTIDISCIPLINARIO DE BIOLOGIA VEGETAL
Unidad Ejecutora - UE
artículos
Título:
Chemical and bioactivity of flavanones obtained from roots of Dalea pazensis Rusby
Autor/es:
MARÍA G. ORTEGA; MENDOZA CATERINE S; MARIANA ANDREA PERALTA; MARÍA G. ORTEGA; JOSÉ L. CABRERA; MARIANA ANDREA PERALTA; JOSÉ L. CABRERA; MARIA DANIELA SANTI; MARIA DANIELA SANTI; MENDOZA CATERINE S
Revista:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2017 vol. 27 p. 1789 - 1794
ISSN:
0960-894X
Resumen:
Two new prenylated flavanones, pazentin A (3?,4?-dihydroxy-6,2?-diprenylpinocembrin, 1) and pazentin B [4?-hydroxy-2?-methoxy-5?- (1???, 1???-dimethylallyl)-6-prenylpinocembrin, 2] together with two known ones (3 and 4) previously isolated from other Dalea species were obtained from the benzene extract of Dalea pazensis Rusby roots. The compounds were evaluated in vitro for their inhibition on mushroom tyrosinase enzyme and in relation to their effect on melanogenesis in B16 murine melanoma cells, by using a spectrophotometric method. The information obtained could be relevant to the knowledge of the structure-activity relationship for these flavonoids with the aim to explore the rational design for skin-whitening agents.