IMBIV   05474
INSTITUTO MULTIDISCIPLINARIO DE BIOLOGIA VEGETAL
Unidad Ejecutora - UE
artículos
Título:
A Database on the Stability of Silver and Gold Nanostructures for Applications in Biology and Biomolecular Sciences
Autor/es:
M. JAZMÍN SILVERO; HASITHA DE ALWIS WEERASEKERA; JUAN C. SCAIANO; DALIANE REGIS CORREA DA SILVA
Revista:
Biomaterials Science
Editorial:
Royal Society of Chemistry
Referencias:
Año: 2016
ISSN:
2047-4830
Resumen:
Colloidal stability of nanoparticles in biological media is an important consideration, when trying to ensure reliable data interpretation of in vitro and in vivo systems. We have developed a detailed colloidal stability library of newly synthesized gold, silver and gold-core silver-shell plasmonic nanoparticles, stabilized with aspartame, glucosamine and sucralose, in various biologically relevant buffers and bacterial and mammalian cell culture media. The stabilizer selection reflects the preference for molecules that are non-toxic, inexpenseive, readily available, water soluble and easy-to -eplace if that is the end-user preference. An on-line resource provides detailed stability information on each of the 81 systems examined. To illustrate how to utilize this stability library, we conducted bacterial toxicity and biocompatibility experiments through the use of one specific set of nanomaterials in the presence and absence of plasmonic irradiation.