A Simple and Accurate Method for Simulation of Hollow Fiber Biochemical Membrane Reactors

GONZO E.E: AND GOTTIFREDI JC

BIOCHEMICAL ENGINEERING JOURNAL

Elsevier

Lugar: Holanda; Año: 2007 vol. 37 p. 80 - 85

1369-703X

A recently developed technique to estimate effectiveness factor in catalytic pellets [J.C. Gottifredi, E.E. Gonzo, On the effectiveness factor calculation for a reaction-diffusion process in an immobilized biocatalyst pellet, Biochem. Eng. J. 24 (2005) 235–242] is used to greatly simplify the simulation of membrane biocatalyst reactors. The whole problem is reduced to well-known plug flow packed bed reactor after an appropriate definition of an effectiveness factor (ç) that takes into account chemical consumption in the catalytic region and mass transfer resistances of the reactive component. A standard R–K routine can then be applied since, at each mesh point, ç is calculated through a non-linear algebraic equation. Results produced with this procedure compare fairly well with previous findings. Moreover some experimental results of kinetics studies related with enzyme immobilization are used to simulate membrane hollow fiber reactors and conversion, concentrations and ç profiles along reactor axial position. The procedure can be applied to any biocatalytic system provided a single chemical reaction takes place although the kinetic expression can be arbitrary.ç) that takes into account chemical consumption in the catalytic region and mass transfer resistances of the reactive component. A standard R–K routine can then be applied since, at each mesh point, ç is calculated through a non-linear algebraic equation. Results produced with this procedure compare fairly well with previous findings. Moreover some experimental results of kinetics studies related with enzyme immobilization are used to simulate membrane hollow fiber reactors and conversion, concentrations and ç profiles along reactor axial position. The procedure can be applied to any biocatalytic system provided a single chemical reaction takes place although the kinetic expression can be arbitrary.ç is calculated through a non-linear algebraic equation. Results produced with this procedure compare fairly well with previous findings. Moreover some experimental results of kinetics studies related with enzyme immobilization are used to simulate membrane hollow fiber reactors and conversion, concentrations and ç profiles along reactor axial position. The procedure can be applied to any biocatalytic system provided a single chemical reaction takes place although the kinetic expression can be arbitrary.ç profiles along reactor axial position. The procedure can be applied to any biocatalytic system provided a single chemical reaction takes place although the kinetic expression can be arbitrary.