INIQUI 05448
INSTITUTO DE INVESTIGACIONES PARA LA INDUSTRIA QUIMICA
Unidad Ejecutora - UE
artículos
Título:
Analysis of the circulation of hepatitis A virus in Argentina since vaccine introduction
Autor/es:
MARÍA D. BLANCO FERNÁNDEZ; C. TORRES; GABRIELA RIVIELLO-LÓPEZ; HUGO R. POMA; VERÓNICA B. RAJAL; SILVIA NATES; DANIEL CISTERNA; RODOLFO H. CAMPOS; VIVIANA A. MBAYED
Revista:
JOURNAL OF CLINICAL VIROLOGY : THE OFFICIAL PUBLICATION OF THE PAN AMERICAN SOCIETY FOR CLINICAL VIROLOGY.
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2012 vol. 18 p. 548 - 551
ISSN:
1386-6532
Resumen:
Hepatitis A virus (HAV) has shown intermediate endemicity in Argentina, but its incidence has decreased since vaccine introduction in 2005. Environmental surveillance was conducted in five rivers from Argentina from 2005 to 2012, complementing clinical information. HAV detection decreased since 2005, although its circulation continues, maintaining viral diversity but not undergoing antigenic drift. Most sequences belonged to subgenotype IA, closely related to Argentinean clinical sequences, but one belonged to proposed subgenotype IC, previously undetected in the country. Environmental surveillance might contribute to monitoring the single-dose vaccination schedule, representing not only strains causing disease but also the circulating population and the viral introductions.
