INSTITUTO DE INVESTIGACIONES EN ENERGIA NO CONVENCIONAL
Unidad Ejecutora - UE
capítulos de libros
Roles of Host and Pathogen Mobility in Epidemic Outbreaks: Mathematical, Modeling and Epidemiological Challenges
CARLOS CASTILLO-CHAVEZ, JUAN PABLO APARICIO, JOSE F. GIL
BIOMAT 2011. International Symposium on Mathematical and Computational Biology
Año: 2012; p. 204 - 220
Finding and developing macroscopic descriptions for the dynamics of large ensem-bles of highly mobile host and/or pathogens subject to modern forms of dispersalpose tremendous challenges to researchers involved in the development and im-plementation of local, regional, national and global public health policies in thepresence of often unexpected, threats of undetermined or uncertain origin. In ad-dition, the study of the dynamics of highly mobile host and/or pathogens provideopportunities for the computational, modeling and mathematical communities inmany directions that include ¯nding new ways of applying existing mathematicalmethods or through the development of new modeling frameworks. Moreover, thechallenges involved in dissecting complex systems have generated opportunities tomathematicians in applied and pure mathematics. Further, recent advances incomputation (hardware, software and theory) mean that today we" are no longercommitted just to the study of simple systems or at best the study of complexsystems over limited windows" in time and space. Today, we can, in fact, applycontinuous advances in the computational sciences to the solution of problems atthe interphase of the life and social sciences. That is, the study of systems whosedynamics are driven by processes that take place over multiple temporal and spa-tial scales; systems that in addition, must routinely account for the inherent levelsof heterogeneity of its biological components. This manuscript, and its compan-ion, Change in Host Behavior and its Impact on the Transmission Dynamics ofDengue" (F. Sanchez, D. Murillo and Castillo-Chavez, this volume) highlights someof the challenges in the context of the dynamics of vector-transmitted diseases, par-ticularly dengue. It is the hope that these contributions will motivate membersof this community, particularly those who are new to the field of mathematicalbiology, to tackle the challenges posed by the study of complex systems.