Bovine mastitis prevention: histopathological effect of lactic acid bacteria inoculated intramammarily at dry off

NADER-MACIAS, MEF; SANTAMARINA S.; PELLEGRINO M.; BERARDO N.; BOGNI C.

San Miguel de Tucumán

Simposio; V Simposio Internacional de Bacterias Lácticas (SIBAL); 2016

CERELA

Bovine mastitis, one of the most prevalent and expensive diseases, occurs when pathogenic bacteria are able to enter in the udder, establish an infection there and produce inflammation of the secretory tissue. Dry cow therapy is one of the recommended methods to cure existing intramammary infections and to prevent new ones at the peripartum period where animals are most susceptible to new infections. An interesting alternative approach to prevent bovine mastitis is the intramammary application of microorganisms with beneficial properties, in order to restore the ecological balance of the udder and protect the host from pathogens. In previous reports, two Lactic Acid Bacteria (LAB) strains isolated from bovine milk were selected: Lactobacillus perolens CRL1724 that showed the best probiotic properties and Lactococcus lactis subsp. lactis CRL1655 that is a bacteriocinogenic strain and produce nisin Z. The aim of the present study was determine the histopathological effect of the two LAB intrammamarily inoculated at dry off. Additionally, the antimicrobial activity of some compounds to be included in a future product containing the selected LAB, was determined. Four quarters bacteriologically negative and with a SCC