CERELA   05438
CENTRO DE REFERENCIA PARA LACTOBACILOS
Unidad Ejecutora - UE
capítulos de libros
Título:
Folate production by lactic acid bacteria
Autor/es:
LEBLANC J-G.,; SAVOY DE GIORI, G.,; LAIÑO, J.
Libro:
Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease
Editorial:
Elsevier
Referencias:
Lugar: Oxford ; Año: 2013; p. 251 - 270
Resumen:
Folate, an essential B-group vitamin, is involved in many metabolic pathways such as energy usage and DNA and RNA biosynthesis. Human beings cannot synthesize folate so an exogenous supply of this vitamin is necessary to prevent nutritional deficiency. A few years ago, extensive studies have shown the health benefits associated with increased folic acid intakes and by consequence many countries now possess mandatory folate enrichment programs. Nowadays, a lot of studies have put into evidence that high intakes of folic acid, the synthetic form of folate, but not natural folates, can cause adverse effects in some individuals such as the masking of the hematological manifestations of vitamin B12 deficiency. Currently, many researchers are evaluating novel methods alternatives to increase concentrations of naturally occurring folate in foods. This review will focus on metabolism, supplementation and production of folate by lactic acid bacteria. The proper selection and use of folate producing microorganisms is an interesting strategy to increase natural folate levels in foods.