Probiotic bacteria as mucosal immune system adjuvant

MALDONADO GALDEANO, CAROLINA; DOGI, CECILIA; BIBAS BONET, MARÍA EUGENIA; DE MORENO DE LEBLANC, ALEJANDRA; PERDIGON, GABRIELA

Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease

Elsevier

Lugar: SAN DIEGO; Año: 2012; p. 285 - 299

The probiotic microorganisms confer a positive impact in health and improve the host immune system. Studies in animals or humans demonstrated that probiotic bacteria can immunomodulate the systemic and mucosal immunity, protect against enteropathogens or offered antitumoural activities and improve health in immunosuppressed host by malnutrition or drug therapy. The probiotic bacteria interact with the intestinal epithelial cells, stimulate the intestinal immune cells and the immune cells of others mucosal distant sites.  It was established the safety of long-term of probiotics or fermented milks consumption, and the influence of the bacteria-free fraction from fermented milk as gut mucosal immune adjuvant.