CERELA   05438
CENTRO DE REFERENCIA PARA LACTOBACILOS
Unidad Ejecutora - UE
capítulos de libros
Título:
Porcine toll-like receptors and their crosstalk with immunobiotics: impact in the regulation of gut inflammatory immunity
Autor/es:
VILLENA JULIO; ASO HISASHI; ALVAREZ SUSANA; KITAZAWA HARUKI
Libro:
Probiotics: Sources, Types and Health Benefits
Editorial:
NOVA Science publishers
Referencias:
Año: 2011;
Resumen:
Intestinal epithelial cells (IECs) and immune cells express a range of pattern recognition receptors
(PRRs) that are specialized to recognize microbe-associated molecular patterns (MAMPs) present
in microbials. The best characterized are the Toll-like receptors (TLRs) which play a key role in
pathogen recognition and the induction of innate effectors and inflammation. Moreover, recent
findings suggest that TLRs are important in intestinal homeostasis and appear to play a role in
tolerance to foreign antigens and commensal bacteria as well as in the immunomodulatory effect
of immunobiotics within probiotics. In recent years, there has been a growing interest in the
swine immune system because of the economic importance of swine as livestock and also its
possible use as a model for the human immune system. In this review article, we summarized our
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
swine immune system because of the economic importance of swine as livestock and also its
possible use as a model for the human immune system. In this review article, we summarized our
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
swine immune system because of the economic importance of swine as livestock and also its
possible use as a model for the human immune system. In this review article, we summarized our
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
swine immune system because of the economic importance of swine as livestock and also its
possible use as a model for the human immune system. In this review article, we summarized our
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
In recent years, there has been a growing interest in the
swine immune system because of the economic importance of swine as livestock and also its
possible use as a model for the human immune system. In this review article, we summarized our
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
In this review article, we summarized our
recent research on the immunoregulatory effects of immunobiotic lactic acid bacteria (LAB) via
porcine TLRs. We described the development of molecular immunoassay systems that allow the
selection of immunobiotic LAB and immunostimulatory DNA sequences from immunobiotics via
porcine TLR signaling. In addition, we described the development of in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.
in vitro systems using a
clonal porcine intestinal epitheliocyte cell line (PIE cells) which could be a useful tool for the
study of TLR activation on IECs, for the selection of immunobiotic LAB strains with specific
immunoregulatory properties and for studying the certain mechanisms of immunobiotic action.