CERELA   05438
CENTRO DE REFERENCIA PARA LACTOBACILOS
Unidad Ejecutora - UE
artículos
Título:
Singlet oxygen quenching and radical scavenging capacities of structurally related flavonoids present in Zuccagnia punctata Cav
Autor/es:
MORÁN VIEYRA, FAUSTINO; BOGGETTI, HÉCTOR; ZAMPINI, IRIS; ORDOÑEZ, ROXANA; ISLAS, MARÍA; ALVAREZ, ROSA; DE ROSSO, VERIDIANA; MERCADANTE, ADRIANA; BORSARELLI, CLAUDIO
Revista:
FREE RADICAL RESEARCH
Editorial:
Informa UK Ltd.
Referencias:
Año: 2009 vol. 43 p. 553 - 564
ISSN:
1071-5762
Resumen:
The singlet oxygen (1O2) quenching and free radical (DPPH, ABTS+ and O2−) scavenging ability of three structurally related flavonoids (7-hydroxyflavanone HF, 2,4-dihydroxychalcone DHC and 3,7-dihydroxyflavone DHF) present in the Argentinean
native shrub Zuccagnia punctata Cav. were studied in solution by combining
electrochemical and kinetic measurements, mass spectroscopy, end-point antioxidant
assays and computational calculations. The results showed that the antioxidant
properties of these flavonoids depend on several factors, such as their electron- and
hydrogen atom donor capacity, the ionization degree of the more acidic group,
solvatation effects and electrostatic interactions with the oxidant species. The theoretical
calculations for both the gas and solution phases at the B3LYP level of theory for the
Osanger reaction field model agreed with the experimental findings, thus supporting the
characterization of the antioxidant mechanism of the Z. punctata flavonoids.