CERELA   05438
CENTRO DE REFERENCIA PARA LACTOBACILOS
Unidad Ejecutora - UE
artículos
Título:
Functional goat milk cheese with feruloyl esterase activity
Autor/es:
ABEIJÓN MUKDSI C; HARO C; GONZÁLEZ S; MEDINA R
Revista:
Journal of Functional Foods
Editorial:
Elsevier
Referencias:
Año: 2013 vol. 5 p. 801 - 801
ISSN:
1756-4646
Resumen:
The aim of this paper is to evaluate the effect of the intake of goat milk cheese manufactured with Lactobacillus fermentum CRL1446 on intestinal feruloyl esterase (FE) activity and oxidative status in Swiss albino mice. This strain was used as single-strain culture (CRL cheese), and in combination with a starter culture (Mix cheese). In both cheeses, L. fermentum reached 8-9 log cfu/g of cheese, and FE  activity increased during ripening. Highest activity level was observed in Mix cheese.  In vivo studies showed that total intestinal FE activity in mice fed with CRL and Mix cheeses increased 1.5 and 2 times compared to non-treated mice, respectively. Administration of Mix cheese produced a two-fold increase in FE activity of small and large intestine mucosa. Mice receiving this cheese also showed a 30% decrease in plasmatic lipoperoxide levels, and an approx. three-fold increase in glutathione reductase activity. Goat milk cheeses elaborated with the FE-producing strain L. fermentum CRL1446 could represent a novel functional food with FE activity, responsible for increasing intestinal FE activity and consequently the bioavailability of antioxidant ferulic acid in the gut, thus enhancing the oxidative status. This functional cheese would represent an innovative product providing protection against oxidative stress-related disorders.