CENTRO DE REFERENCIA PARA LACTOBACILOS
Unidad Ejecutora - UE
EFFECT OF GALLIC ACID AND CATECHIN ON Escherichia coliI GROWTH PARAMETERS
RODRIGUEZ VAQUERO M.J; MANCA DE NADRA M.C.
Lugar: Argentina; Año: 2006 vol. 30 p. 177 - 177
Phenolic compounds are categorized into subgroups, flavonols, non- flavonols and tannins. They have attracted much interest recently because many studies suggest that they have a variety of beneficial biological properties, which may play an important role in the maintenance of human health. The aim of this work was to investigate the effect of two phenolic compounds; the non flavonoid gallic acid and the flavonoid catechin on the growth of Escherichia coli ATCC 35218, a bacterium that may cause human infections. Growth experiments were performed in nutrient broth and agar medium. Phenolic compounds were added to the medium to obtain a final concentration of 25, 50, 100, 200 and 500 mg/l. At 25 mg/l, gallic acid and catechin produced 19 and 33% of inhibition on the growth rate, and 11 and 22% inhibition on final cell density, respectively. Gallic acid and catechin decreased the number of viable cells 44 and 72%, respectively. The bacterium growth inhibition increased with the concentration of phenolic compounds. Catechin was the inhibitoriest phenolic compounds. This phenolic compound could be considered as a potential natural inhibitor of this pathogenic bacterium.