Dietary restriction in bone formation in alveolar bone modeling and remodeling (Abstract)

GARAT, J; PANI, M; LOPEZ-MIRANDA, J; RUIZ HOLGADO, N; MEHERIS, H; GAUFFIN CANO, PAOLA; GONZALEZ, S

BIOCELL

Lugar: Mendoza-Argentina; Año: 2006 vol. 30 p. 205 - 205

0327-9545

160. DIETARY RESTRICTION IN BONE FORMATION IN ALVEOLAR BONE MODELTNG AND REMODELING  This work examined the influence of the dietary restriction in al· veolar bone modeling and remodeling in growing mice. Twenty weaned Balb/C mice 17 days age were assigned to one of 2 groups. Control (n=l0) and undernourished (n=10). Controls was fed with a conventional hard diet. Undernourished was fed with 75% of the amount of the diet of the control group. The corporal weight was registered in periodic formon At 25 days of experience, the animals were sacrificed, mandibles were disected and procesed for embed­ded in paraffin. Buccolingually sections of the mesial root of the first molar were made and stained with H-E. Sections were photo­graphed and tracings were performed for the histomorphometrical study. The following parameters were evaluated following stereo­logical principIes: percentage ofbone reabsorción, bone fonnation and bone rest surfaces, considering the 100% the total area of the remodeling and modeling alveolar bone walls respectively. Corpo­ral weights were significantly smaller in the undernourished ani­mals. The histomorphometrical study shows that dietary restric­tion produced an alterat10n in the process of bony modeling and remodeling characterized by an increase ofthe bony surfaces cov­ered by lining cells (rest) associated to the statistically significant reduction of surfaces covered by osteoblasts (p<0,05).