CERELA   05438
CENTRO DE REFERENCIA PARA LACTOBACILOS
Unidad Ejecutora - UE
artículos
Título:
Probiotics for Everyone! The Novel Immunobiotic Lactobacillus rhamnosus CRL1505 and the Beginning of Social Probiotic Programs in Argentina
Autor/es:
VILLENA JULIO; SALVA SUSANA; NÚÑEZ MARTHA; CORZO JOSEFINA; TOLABA RENÉ; FAEDDA JULIO; FONT GRACIELA; ALVAREZ SUSANA
Revista:
International Journal of Biotechnology for Wellness Industries
Editorial:
Lifescience Global
Referencias:
Lugar: Kuala Lumpur; Año: 2012 vol. 1 p. 189 - 189
ISSN:
1927-3037
Resumen:
Lactobacillus rhamnosus CRL1505 (Lr1505) stimulates immune responses in the gut and in the respiratory tract and improves resistance against Salmonella typhimurium and Streptococcus pneumoniae infections in immunocompetent and immunocompromised mice. Considering that respiratory infectious diseases continue to be a major cause of death among preschool children in developing countries, the aim of the present study was to evaluate the effect of Lr1505 on the health of children. A randomized-controlled double-blind clinical trial in 298 healthy children (2-5 years old), attending daycare centers was performed. Yogurt containing Lr1505 was administered to children for 6 months (five times a week). Results were statistically compared with those of children from the same community that received a placebo yogurt (without probiotic). Administration of Lr1505 to young children reduced the incidence of infections: 66% of children in the placebo group presented symptoms of infection while only 34% of cases were detected in the Lr1505 group. Significant differences (P