Specific probiotic for health control of goat

APAZ, ANA; LAZARTE, SILVIA SFER; OQUILLA, JUANA DEL VALLE; DIB, JULIÁN RAFAEL; GONZALEZ, F; DUPRAZ, J; ARENA, MARIO; GONZALEZ, SILVIA

Tucumán

Simposio; III Simposio Internacional de Bacterias L¨¢cticas; 2009

The use of ionophore polyether-antibiotics as growth promoters and/or anticoccidial agents, for ruminants accuses a net gain in energy that becomes weight gain/day, with improvement in the rate of food conversion. The emergence of antibiotic resistant strains is a problem, but the most important issue is that, via food chain, this resistance may occur by transferring from animals to humans. Thus, pharmacologically active substances must be studied about toxicological significance, to establish the "no observed adverse effect level" (NOAEL) and the "acceptable daily intake" (ADI) for humans. Given these requirements, probiotics as growth promoters and / or health, are a sound alternative. At present, parasite control in goats has no system (traditional or alternative) with a solution for protozoa (coccidia) and metazoa (nematoda). Our group has designed a probiotic for nematode control in goats, but similar to drugs, the coccidia showed resistance. Thus, for over 4 years, our aim-work was the selection of a host-specific probiotic strain with anti-Eimeria ability. The in vivo assay was carried out from weaning to rumen development.  30 goats (15 animals/group), received conventional diet (Control Group) or a probiotic mixture (anti nematoda+anti coccidia) and the protocol of administration (10 ingesta/days - 5 rest/days) was maintained during 40 days. Preliminary results showed that Enterococcus sp was able to completely avoid the presence of this unicellular parasite with efficiency ¡Ö 14%. In addition, the Treated Group showed, compared to Control, significant differences in enterobacteria reduction, weight gain, conversion rate and profile of serum immunoglobulins. Currently, assays to achieve greater efficiency about anti-Eimeria activity are in progress.