Repellent activity of polymer system containing essential oil Acantholippia Trifida (Gay) Moldenke

ZYGADLO J.; ABRAHAM G.A.; LÓPEZ S.; MÁRQUEZ J; CORTEZ TORNELLO P.R.; TAPIA A.; STARIOLO R

Mendoza

Encuentro; XXXVII Reunión Científica Anual Sociedad de Biología de Cuyo; 2019

Sociedad de Biología de Cuyo

The essential oils (EO) are being developed as repellents against insects. Essential oils have been presented as an alternative in the control of insect pests due to its low toxicity in mammals, little residual life in the environment, and fewer requirements imposed by the legal framework, because they enjoy social acceptance due to the widespread use of aromatic species. The repellents, although they do not kill the insect, are a good preventive alternative to avoid the bite of the vectors. The use of repellents against Triatoma infestans vector might help prevent, or at least reduce, Chagas? disease transmission. The EO from the Andean flora have shown excellent repellent activity againt nymphs of T. infestans, effect that could be extended by its incorporation into polymeric systems, which is considered an adequate strategy of controlled release of the active substance. This study investigated the possibility of increasing the duration of repellence activity of essential oils A. trifida, by incorporating into inexpensive poly (e-caprolactone -PCL) polymer. Aerial part of A. trifida, were collected from San Juan, Argentina, during the 2018-2019 flowering period and were hydrodistilled to obtain the EO in a Clevenger type apparatus for 1 h, according to the method recommended by the European Pharmacopoeia and characterized by GC-FID and GC/MS analyses. Repellency on T. infestans nymphs was determined following to a standard method. Polymeric systems with different morphology (films and microparticles) were preparated by incorporation of selected essential oils, according to previously reported methodologies. The polymeric systems (PCL + essential oil of A. trifida) showed a marked repellency on T. infestans nymphs (50 at 80 %) included in class III and IV respectively, in the doses tested and also greater durability over time. Authors are grateful to Serv. Nac. Chagas, Cba. For providing T. infestans nymphs, CICITCA-UNSJ, and UNMdP.