INTEMA   05428
INSTITUTO DE INVESTIGACIONES EN CIENCIA Y TECNOLOGIA DE MATERIALES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Chitosan-based films with vanillin: optimization of formulation by response surface methodology
Autor/es:
PONCE, A.; TOMADONI, B.; PEREDA, M.; ANSORENA, R.
Lugar:
Bahía Blanca
Reunión:
Congreso; CAIQ 2017 IX Congreso Argentino de Ingeniería Química; 2017
Institución organizadora:
Asociación Argentina de Ingenieros Químicos
Resumen:
The objective of this work was to optimize the formulation of chitosan films with vanillin as a cross-linking agent, to simultaneously improve their physical, barrier and mechanical properties. Three factors were studied at three levels: vanillin content (0, 25 and 50% w/w chitosan), glycerol content (30, 45 and 60% w/w chitosan) and drying temperature (35, 50 and 65°C). Response surface methodology (RSM) and desirability function were used to find the optimal levels of each factor that simultaneously optimize opacity values, Young modulus (E), T0 and Tmax parameters (obtained from TGA analysis) and water vapor permeability (WVP) of the films. Fifteen formulations combining the studied factors were prepared according to a Box-Behnken design. All the independent variables exhibited significant effects on the film properties. Vanillin linear effect was significant on every response, except WVP. Drying temperature also significantly affected T0, E and WVP in linear terms, while glycerol lineal term significantly affected E and Tmax. The quadratic regression coefficient of vanillin only showed a significant effect on WVP, while glycerol quadratic level affected Tmax and WVP. The only significant interaction effect found was glycerol x vanillin, which affected Tmax value. An optimal chitosan film formulation was found, with vanillin content of 25% w/w, glycerol content of 45% w/w and drying temperature of 65ºC. RSM approach using the desirability function was found to be an effective tool to investigate changes in films properties and to search for the optimal active chitosan film formulation with a natural cross-linking agent, such as vanillin.