INTEMA   05428
INSTITUTO DE INVESTIGACIONES EN CIENCIA Y TECNOLOGIA DE MATERIALES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Characterization Novel microbial cellulose/alginate composite for biomedical applications: synthesis and characterization
Autor/es:
MAXIMILIANO CACICEDO; L LEON; JIMENA GONZALEZ; VERA ALEJANDRA ALVAREZ; L PORTO; GUILLERMO CASTRO
Reunión:
Simposio; 10th European Symposium on Biochemical Engineering Sciences and 6th International Forum on Industrial Bioprocesses; 2014
Resumen:
Bacterial cellulose (BC) is an extracellular hydrophilic polysaccharide produced by Gluconacetobacter hansenii and others microorganisms. The unique nanofibrillar structure has a high water content (99%) and displays distinctive properties such as purity, elevated degree of polymerization (up to 8,000 kDa.), high crystallinity, and mechanical stability[1]. BC has a nanofibrillar organization that mimics extracellular matrix, particularly collagen which is relevant for many biomedical uses. Besides, this biomaterial has been widely studied for wound healing and tissue engineering.[2] In relation with that, one of the main strategies for bacterial cellulose films modification is the in situ modification which consist in supplementing molecules in culture media to be integrated in the matrix. The film is produced and acquired different properties.[3] In this sense, BC films where produced in presence of sodium alginate for the synthesis of an hybrid biomaterial suitable to work as a Local Drug Delivery System for biomedical applications.