Positron Annihilation Spectroscopy as a Tool to Determine Nanosized Voids in Tumours

C. Y. CHAIN; GALLE MARIANELA; GARCIA DE BRAVO M; DAMONTE LC; A. F. PASQUEVICH

Gijon

Simposio; 18th International Symposium on Metastable, Amorphous and Nanostructured Materials, (ISMANAM 2011); 2011

Novel Positron Annihilation Lifetime Spectroscopy applications include the study of tumour tissues. In order to obtain reliable information from these investigations, a rigorous analysis of the adequate working conditions is necessary. We report here preliminary experiments in tumours, fixed in different manners and measured both using a standard 22Na positron source and as 22Na impregnated samples. Results suggest that tumour formol fixation and the using of a positron source are good strategies to perform these determinations. Experiments reveal the existence of a tumour characteristic long lived lifetime which was assigned to ortho-positronium annihilation in protein cavities.