INIBIOLP   05426
INSTITUTO DE INVESTIGACIONES BIOQUIMICAS DE LA PLATA "PROF. DR. RODOLFO R. BRENNER"
Unidad Ejecutora - UE
artículos
Título:
Expresion analysis of genes putatvely associated with hygienci behvior in selectd stocks of Apis mellfera L of argentina
Autor/es:
LANZAVECHIA SILVIA; SOTO G; LANZAVECHIA SILVIA; SOTO G; MARÍA ALEJANDRA PALACIO; SCANNAPIECO ALEJANDRA ; MARÍA ALEJANDRA PALACIO; CLADERA ; SCANNAPIECO ALEJANDRA ; MANNINO M C ; CLADERA ; MANNINO M C
Revista:
INSECTES SOCIAUX
Editorial:
BIRKHAUSER VERLAG AG
Referencias:
Lugar: BASEL; Año: 2018 vol. 64 p. 485 - 494
ISSN:
0020-1812
Resumen:
Hygienic behavior is an economically beneficial,heritable trait, which has evolved to limit the impact of honeybee pathogens. Selecting and breeding colonies with high levels of hygienic behavior has become a feasible andenvironmentally friendly strategy to control brood diseases in honeybee colonies worldwide. The identification of genes involved in the expression of this character may not only unravel molecular and biochemical pathways underlyinghygienic behavior, but also serve as a practical approach to select disease resistance biomarkers useful for honeybee breeding programs. In the present work, we evaluated, at genetic level, Apis mellifera stocks selected for hygienic behavior, widely used for commercial apiculture in Argentina. We analyzed the expression profiles of five genes previously identified as candidates associated with hygienic behavior both in QTL and global gene expression studies in honeybees, more precisely, involved in perceptionand processing of olfactory information. We validated the differential expression of these genes as potentially responsible for behavioral differences in our selected stocks. Our results indicate that four of them (octopaminereceptor, smell-impaired, odorant-binding protein 3, and odorant-binding protein 4) were differentially expressed between hygienic and non-hygienic bees within our highly hygienic colonies. The present findings improve our understanding of the molecular mechanisms underlying the differentiation of middle-age worker bees in their genetic propensity to perform hygienic behavior. This progresstowards the genetic characterization of highly hygienic colonies that are commercially used in Argentine apiculture lays the groundwork for future development of targets for marker-assisted selection of disease-resistant honeybee stocks