CINDECA   05422
CENTRO DE INVESTIGACION Y DESARROLLO EN CIENCIAS APLICADAS "DR. JORGE J. RONCO"
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
A green method for β-aminocrotonates synthesis
Autor/es:
L. SANCHEZ; G. SATHICQ; G. BARONETTI; H. THOMAS; G. ROMANELLI
Lugar:
Foz do Iguaçu
Reunión:
Conferencia; 4th International IUPAC Conference on Green Chemistry ? 4th ICGC ? August 25-29, 2012-Foz do Iguaçu, Brazil.; 2012
Resumen:
β-aminocrotonates are versatile intermediates for the synthesis of many heterocycles. Also, β-aminocrotonates have been previously evaluated as compounds with potent oral anticonvulsant activity at the voltage-dependent Sodium channel binding site in a manner similar to class 1 anticonvulsants Phenytoin, Carbamazepine, and Lamotrigine1. Continuing with our studies about Green Methodologies, we now present our findings about the catalytic preparation of crotonates using Wells-Dawson heteropolyacids under solvent-free conditions.  
rds']