Enantioselective hydrogenation of acetophenone with organogermanium-modified chiral heterogeneous catalysts

VIRGINIA VETERE; MARÍA B. FARAONI; JULIO C. PODESTÁ; MÓNICA L. CASELLA

Munich

Congreso; 15th International Congress on Catalysis 2012; 2012

DECHEMA - The Society for Chemical Engineering and Biotechnology

As part of our ongoing studies on the preparation of bimetallic catalysts derived from chiral organometallic compounds in order to use them in heterogeneous catalysis [1,2], we consider it of interest to carry out the preparation of bimetallic systems derived from chiral organogermanium compounds and Pt supported on SiO2. Bimetallic systems were prepared by controlled surface reactions, using techniques derived from the Surface Organometallic Chemistry on Metals (SOMC/M) [3]. A key step in the preparation of asymmetric heterogeneous catalysts based on silica-supported platinum chemically modified with chiral organometallic compounds is the synthesis of optically pure organometallic derivatives. In this contribution, we report the enantioselective hydrogenation of acetophenone using a catalytic system composed of Pt modified with tri-(-)-menthylmethylgermanium (1) and tri-(-)-menthylgermanium hydride (2).