CINDECA 05422
CENTRO DE INVESTIGACION Y DESARROLLO EN CIENCIAS APLICADAS "DR. JORGE J. RONCO"
Unidad Ejecutora - UE
artículos
Título:
Solvent-free approach to 3,4-dihydropyrimidin-2(1H)-(thio)ones: Biginelli reaction catalyzed by a Wells-Dawson reusable heteropolyacid
Autor/es:
G. ROMANELLI, A. SATHICQ, J. AUTINO, H. THOMAS, G. BARONETTI
Revista:
SYNTHETIC COMMUNICATIONS
Editorial:
Marcel Dekker
Referencias:
Año: 2007 vol. 37 p. 3907 - 3916
ISSN:
0039-7911
Resumen:
The Biginelli reaction is performed in an efficient, simple, solvent-free procedure, using a small amount of H6P2W18O62.24H2O, a reusable heteropolyacid catalyst with WellsDawson structure. Both aromatic and aliphatic aldehydes, and different b-dicarbonyl compounds and urea or thiourea, were used as starting materials. Seventeen examples of dihydropyrimidinones and dihydropyrimidinethiones
