CINDECA   05422
CENTRO DE INVESTIGACION Y DESARROLLO EN CIENCIAS APLICADAS "DR. JORGE J. RONCO"
Unidad Ejecutora - UE
artículos
Título:
QSAR analysis on tacrine-related acetylcholinesterase inhibitors
Autor/es:
K. WONG; A. MERCADER; L. SAAVEDRA; B. HONARPARVAR; G. ROMANELLI; P. DUCHOWICZ
Revista:
JOURNAL OF BIOMEDICAL SCIENCE
Editorial:
BIOMED CENTRAL LTD
Referencias:
Lugar: Londres; Año: 2014 vol. 21 p. 84 - 92
ISSN:
1021-7770
Resumen:
The evaluation of the clinical effects of Tacrine has shown efficacy in delaying the deterioration of the symptoms of Alzheimer?s disease, while confirming the adverse events consisting mainly in the elevated liver transaminase levels. The study of tacrine analogs presents a continuous interest, and for this reason we establish