CENTRO DE INVESTIGACION Y DESARROLLO EN CIENCIAS APLICADAS "DR. JORGE J. RONCO"
Unidad Ejecutora - UE
Pt-based chiral organotin modified heterogeneous catalysts for the enantioselective hydrogenation of 3,4-hexanedione
VIRGINIA VETERE; MARÍA B. FARAONI; JULIO C. PODESTÁ; MÓNICA L. CASELLA
APPLIED CATALYSIS A-GENERAL
ELSEVIER SCIENCE BV
Lugar: Amsterdam; Año: 2012 vol. 445 p. 209 - 209
In this paper we have studied the liquid-phase enantioselective hydrogenation of 3,4-hexanedione using Pt-based catalysts, modified with chiral organotin compounds derived from the (-)-menthyl group: (-)-Pt-MenSnBu3 and (-)-Men3Sn-Sn-(-)-Men3. The organotin chiral modifiers were carefully synthesized and characterized in order to obtain optically pure compounds. The catalysts were prepared through a controlled surface reaction between the supported transition metal and the organometallic compound, using techniques derived from Surface Organometallic Chemistry on Metals (SOMC/M). The organobimetallic catalytic systems were found to be active and enantioselective in the hydrogenation of 3,4-hexanedione, yielding an enantiomeric excess of 25%?27% for 4-hydroxy-3-hexanone.