Complications and cardiovascular risk factors in people with type 1 diabetes in the International Diabetes Management Practices Study (IDMPS)

RAMACHANDRAN A; ASCHNER P; CHAN J; HANCU N; BAIK SH; FERREIRA S; ILKOVA H; TWIGG S; GAGLIARDINO JJ

Dinamarca

Congreso; 42nd Annual Meeting of the European Association for the Study of Diabetes; 2006

European Association for the Study of Diabetes

Background and Aims: Preliminary data from the IDMPS were used to assess the frequency of chronic complications and associated cardiovascular risk factors in people with type 1 diabetes (Q18 years) from 11 countries in Eastern Europe, Asia, and Latin America. Materials and Methods: This observational study enrolls patients seen in current medical practice by physicians managing diabetic patients. Results: Data are currently available for 1327 people (51% men) with type 1 diabetes who had a mean age of 36T13 years and a mean disease duration of 11 years. 18% were smokers. Mean HbA1c was 8.2T1.96% and 27% of people had an HbA1c <7%. 98% of people had microvascular complications (56% retinopathy, 45% nephropathy, 72% neuropathy) and 19% had macrovascular complications (10% coronary artery disease, 3% cerebrovascular disease, 11% peripheral vascular disease). Mean systolic/diastolic blood pressure (BP) was 122/75 mmHg. Antihypertensive medication was taken by 20% of people and 47% had achieved a BP below 130/80 mmHg. Target treatment values were achieved for LDL (<100 mg/dL) in 41% of people (11% receiving lipid lowering treatment), for HDL (>40 mg/dL) in 81% of people (18% receiving lipid lowering treatment), and for triglycerides (<150 mg/dL) in 72% of people (10% receiving lipid lowering treatment). Only 3% of people reached all 3 recommended targets for HbA1c, BP and lipids. Conclusion: Thus, although patients have wide access to medications that specifically treat these conditions, it appears that more suitable guidance and education are necessary to ensure their effective use by people with type 1 diabetes world wide.