CENEXA   05419
CENTRO DE ENDOCRINOLOGIA EXPERIMENTAL Y APLICADA
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Hypoglycemia and self-monitoring blood glucose are predictive factors for achieving glycemic control in people with diabetes
Autor/es:
GAGLIARDINO JJ; BAIK SH; CHAN J; FERREIRA S; ASCHNER P; HANCU N; ILKOVA H; TWIGG S; RAMACHANDRAN A
Lugar:
Dinamarca
Reunión:
Congreso; 42nd Annual Meeting of the European Association for the Study of Diabetes; 2006
Institución organizadora:
European Association for the Study of Diabetes
Resumen:
Background and Aims: To identify predictive factors for achieving a target of HbA1c <7% in patients with type 1 (T1DM) and type 2 diabetes (T2DM) world wide, a logistic regression analysis was performed using initial data gathered in the International Diabetes Management Practices Study (IDMPS) in 11 countries (Eastern Europe, Asia, Latin America). Materials and Methods: 1327 people with T1DM and 7543 people with T2DM were recruited; 798 T1DM patients and 3537 T2DM patients were available for the logistic regression analysis. Results: In the overall population, the mean HbA1c was 8.2T1.96% in T1DM patients (27% had an HbA1c <7%) and was 7.7T1.75% in T2DM patients (38% had an HbA1c <7%). It was found that prior hypoglycemia or a fear of hypoglycemia largely decreases the chance that people with diabetes will achieve the HbA1c target: people with T1DM have a 12-times greater chance (95% confidence interval [CI]: 5.106; 28.070) of achieving the target if they did not experience, or are not afraid of, hypoglycemia and the chance is 17-times greater (95% CI: 6.118; 45.769) for people with T2DM. It was also found that self monitoring of blood glucose increased the likelihood of achieving the target of HbA1c in both T1DM patients (2.2-times greater, 95% CI: 0.265; 0.770) and T2DM patients (1.3-times greater, 95% CI:0.648; 0.886). The only other factors found to correlate with achieving the HbA1c target were whether patients had a normal body mass index (20–25 kg/m2), self-adjust their insulin dose, not having a macrovascular complication and had a shorter duration of disease (1–5 years). Conclusion: Thus, the factors most strongly associated with achieving the recommended target of HbA1c <7% in people with either T1DM or T2DM were whether people previously experienced, or were afraid of, hypoglycemia and self-monitoring of blood glucose.