CENEXA   05419
CENTRO DE ENDOCRINOLOGIA EXPERIMENTAL Y APLICADA
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Hypoglycemia and self-monitoring blood glucose are predictive factors for achieving glycemic control in people with diabetes
Autor/es:
ASCHER P; BAIK SH; CHAN J; FERREIRA S; GAGLIARDINO JJ; HANCU N; ILKOVA H; TWIGG S; RAMACHANDRAN A
Lugar:
Washington DC
Reunión:
Congreso; 66th Scientific Sessions of the American Diabetes Association; 2006
Institución organizadora:
American Diabetes Association
Resumen:
To identify predictive factors for achieving a target of HbA¼1c <7% in patients with type 1 (T1DM) and type 2 diabetes (T2DM) world wide, a logistic regression analysis was performed using initial data gathered in the International Diabetes Management Practices Study (IDMPS) in 11 countries (Eastern Europe, Asia, Latin America). 1327 people with T1DM and 7543 people with T2DM were recruited; 798 T1DM patients and 3537 T2DM patients were available for the logistic regression analysis. In the overall population, the mean HbA¼1c was 8.2}1.96% in T1DM patients (27% had an HbA¼1c <7%) and was 7.7}1.75% in T2DM patients (38% had) an HbA¼1c <7%. It was found that prior hypoglycemia or a fear of hypoglycemia largely decreases the chance that people with diabetes will achieve the HbA¼1c target: people with T1DM have a 12-times greater chance (95% confidence interval [CI]: 5.106; 28.070) of achieving the target if they did not experience, or are not afraid of, hypoglycemia and the chance is 17-times greater (95% CI: 6.118; 45.769) for people with T2DM. It was also found that self monitoring of blood glucose increased the likelihood of achieving the target of HbA¼1c in both T1DM patients (2.2-times greater, 95% CI: 0.265; 0.770) and T2DM patients (1.3-times greater, 95% CI: 0.648; 0.886). The only other factors found to correlate with achieving the HbA¼1c target were whether patients had a normal body mass index (20-25 kg/m½2), self-adjust their insulin dose, not having a macrovascular complication and had a shorter duration of disease (1-5 years). Thus, the factors most strongly associated with achieving the recommended target of HbA¼1c <7% in people with either T1DM or T2DM were whether people previously experienced, or were afraid of, hypoglycemia and self-monitoring of blood glucose.