CONICET | Buscador de Institutos y Recursos Humanos

The demand for bioactive ceramics for hard tissue replacement and bone regeneration has increased rapidly due to their biological properties. The conversion of natural spongy bone extracted from animals offers the potential of developing a natural porous hydroxyapatite (Ca10(PO4)6(OH)2,CaHap), structure without the need for using harmful chemicals [1]. This natural porous CaHap has excellent biocompatibility, bioactivity and osteoconduction properties. The aim of this research is to obtain a carbonate apatite from animal bone through a sintering process. Bovine bones were treated with water at 100 ºC and aqueous solutions of NaOH in order to remove the organic parts. The solid obtained sintered in an air atmosphere at different temperatures ranging from 400 ºC to 1000 ºC. The sintered samples were characterized by atomic absorption spectroscopy, Infrared spectroscopy, X ray powder diffraction and scanning electron microscopy (SEM). Unlike to the works published in the literature [2, 3], the results revealed that the thermal stability of the carbonate apatite phase was not disrupted and that all of the sintered samples exhibited phase carbonate apatite with different percent of carbonate. In conclusion, this work shows that the sample sintered until 800 ºC exhibit a most chemical composition and structure that could be exploited to provide good alternatives to synthetic apatite as substituted of tissue bone.Bibliografía1. K. Haberkoet al. J. Eur. Ceram. Soc. 2006;26: 537-42. 2. A.M. Barakat, K.A. Khalil, A. S. Faheem, A.M. Omra, B. Gaihre, S. M. Khil, H. Y. Kim. Materials Science and Engineering C 28 (2008) 1381?1387.3. J. Brzezińska-Miecznik, P. Jeleń, K. Haberko, W. Mozgawa, M. Sitarz. Ceramics International 43 (2017) 12540?12545.