CEQUINOR   05415
CENTRO DE QUIMICA INORGANICA "DR. PEDRO J. AYMONINO"
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
A Theoretical Study of a Family of 2-benzyl-3-methylquinoxaline-1,4-di-N-oxide Derivatives
Autor/es:
E. VICENTE; P.R. DUCHOWICZ; M.G. VITALE; S. PÉREZ-SILANES; I. ALDANA; E.A. CASTRO; R. PIS DIEZ; A. MONGE
Reunión:
Simposio; XXI International Symposium on Medicinal Chemistry; 2010
Resumen:
The quinoxaline derivatives are a class of compounds that showvery interesting biological properties (antibacterial, antiviral,anticancer, antifungal, antihelmintic, and insecticidal). The oxidationof both nitrogens of this heterocyclic system, needed forobtaining quinoxaline 1,4-di-N-oxide derivatives, greatly increasesthe number of biological properties [1]. In fact, recent studieshave demonstrated that quinoxaline 1,4-di-N-oxides areendowed with antimycobacterial, antiprotozoal, and anticandidaactivities as well as mutagenic properties, depending on specificchemical features [1].
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