On the Interaction of Vanadium Species with the Monoisoamyl Ester of meso-2,3-Dimercaptosuccinic Acid

WILLIAMS, PAM; J ZINCZUK; ENRIQUE JOSE BARAN

Biological Trace Element Research

Humana Press

Lugar: Hobocken, NJ, USA; Año: 2010 vol. 134 p. 220 - 225

0163-4984

   The interaction of the VO(2+) cation with the monoisoamyl ester of meso-2,3-dimercaptosuccinic acid (MiADMSA) was investigated by electron absorption spectroscopy in aqueous solutions at different pH-values. The spectral behavior, complemented with a spectrophotometric titration, shows the generation of a [VO(MiADMSA)2](4-) complex in which the oxocation interacts with two pairs of deprotonated -SH groups of the ester. Besides, MiADMSA rapidly reduces VO3(-) to VO(2+), which might be chelated by an excess of the ester, and also produces relatively rapid reduction of V2O5 suspensions at pH = 6.5. The results of this study suggest that MiADMSA might be a potentially useful detoxification agent for vanadium.