CEQUINOR   05415
CENTRO DE QUIMICA INORGANICA "DR. PEDRO J. AYMONINO"
Unidad Ejecutora - UE
artículos
Título:
Chelation Therapies: A Chemical and Biochemical Perspective
Autor/es:
ENRIQUE JOSE BARAN
Revista:
CURRENT MEDICINAL CHEMISTRY.
Editorial:
BENTHAM SCIENCE PUBL LTD
Referencias:
Lugar: Sharjah, Emiratos arabes Unidos; Año: 2010 vol. 17 p. 3658 - 3658
ISSN:
0929-8673
Resumen:
   Chelation therapy occupies a central place in modern medicine and pharmacology, beacuse continuous studies with laboratory animals and extensive clinical experience demonstrate that accute or chronic intoxications with a variety of metals can be considerable improved by administration of a suitable chelating agent. In this review the chemical characteristics, properties and uses of the most common chelating agents as well as those of some new and very promising agents of this type, are discussed. In the second part of the review the biological and biochemical impact of these agents, as well as their use for the treatment of some selected diseases and disorders, are also analyzed and discussed in detail.