CEQUINOR 05415
CENTRO DE QUIMICA INORGANICA "DR. PEDRO J. AYMONINO"
Unidad Ejecutora - UE
artículos
Título:
Spectroscopic Behavior and Biological Activity of K3[VO(O2)2CO3].H2O
Autor/es:
G. ARRAMBIDE, J. RIVADENEIRA, S.B. ETCHEVERRY, B.S. PARAJÓN-COSTA D. GAMBINO, E. J. BARAN
Revista:
BIOLOGICAL TRACE ELEMENT RESEARCH
Editorial:
Humana Press Inc.
Referencias:
Año: 2009
ISSN:
0163-4984
Resumen:
<!-- /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-parent:""; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman"; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US; mso-fareast-language:EN-US;} @page Section1 {size:612.0pt 792.0pt; margin:70.85pt 3.0cm 70.85pt 3.0cm; mso-header-margin:36.0pt; mso-footer-margin:36.0pt; mso-paper-source:0;} div.Section1 {page:Section1;} --> The potassium salt of the carbonato oxodiperoxovanadate(V) complex, obtained by a known synthetic procedure, was thoroughly characterized by infrared, Raman and electronic spectroscopy. The bioactivity of the complex on the cell proliferation was tested on osteoblast-like cells (MC3T3E1 osteoblastic mouse-calvaria derived cells and UMR106 rat osteosarcoma-derived cells) in culture. At low doses the complex is more toxic for the non-transformed osteoblasts than for the tumoral ones, whereas at higher doses the deleterious effects are similar for both cell lines. This peroxo complex seems to be the most toxic compound that has so far been tested on osteoblast-like cells in culture.
